[Home ] [Archive]   [ فارسی ]  
:: Main :: About :: Current Issue :: Archive :: Search :: Submit :: Contact ::
:: Volume 1, Number 1 (Autumn-Winter 2015) ::
3 2015, 1(1): 20-22 Back to browse issues page
Prevalence of HLA-B27 in the group of patients referred to Danesh clinical laboratory
Najmeh Ahangari, Alireza Pourreza , Elaheh Ahangari, Majid Jouybari
Abstract:   (994 Views)

Background: HLA B27 is a sub class of Human leukocyte antigen (HLA) class I molecule. It was known as the first genetic risk factor associating with ankylosing spondylitis (AS). Allele Frequency of HLA-B27 alleles is different across populations. The present study is aimed to investigate the prevalence of HLA-B27 in patients referred to Danesh clinical laboratory during 2014 to 2015. Methods and material: Among 178 patient referred to our lab, 171 data were valid. 5ml blood samples were obtained in heparinized tubes for HLA typing test. Direct typing of the HLA-B27 allele was performed by the standard micro lymphocytotoxity test (MLCT method). Result: A total of 171 patients have been typed for HLA-B27. The prevalence of HLA-B27 positive was found as 16.4%. Conclusion: A national level of HLA B27 prevalence approximation is required for public health management particularly because of recent improvements in diagnostic testing for the disorder

Keywords: HLA B27, Prevalence, Epidemiology, diagnosis
Full-Text [PDF 294 kb]   (618 Downloads)    
Type of Study: Research | Subject: Special
Received: 2015/09/6 | Accepted: 2015/09/6 | Published: 2015/09/6
Send email to the article author

Add your comments about this article
Your username or email:

Write the security code in the box >



XML     Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Ahangari N, Pourreza A, Ahangari E, Jouybari M. Prevalence of HLA-B27 in the group of patients referred to Danesh clinical laboratory. 3. 2015; 1 (1) :20-22
URL: http://mmj.hums.ac.ir/article-1-30-en.html
Volume 1, Number 1 (Autumn-Winter 2015) Back to browse issues page
مجله پزشکی مولکولی Molecular Medicine Journal
Persian site map - English site map - Created in 0.048 seconds with 796 queries by yektaweb 3503