The Molecular Medicine Journal (MMJ) is an international quarterly publication of Hormozgan University of Medical Science of Iran and welcomes contributions from all areas of molecular sciences, including molecular biology, immunology, biochemistry, microbiology, genetics, cell and developmental biology, pharmacology, physiology, medicine etc. In fact, MMJ will accept manuscripts in most areas of molecular and genetic medicine – both basic and applied. Keeping in view the considerable health-related problems faced by the developing nations, particular consideration will be given to articles on applied biomedical issues of the developing world. The Journal is fully peer-reviewed and manuscripts in the following categories will be considered for publication: reviews and mini-reviews, research articles and short research reports, new methods and technologies, opinions on previously published literature and letters to the editor, meeting reports and commercial, patent and product news (inquiries to the Editor). Acceptance of manuscripts for publication depends on their quality, originality, clarity, and relevance to the Journal’s scope.
Manuscript Submission Form
A manuscript submission form “including 1) originality and authorship, 2) copyright assignment, and 3) potential conflict of interest” must be completed for each article submitted. The corresponding author should read the three sections, check the appropriate boxes, sign the document where indicated, and upload the completed form to the manuscript submission system upon article submission. Submissions will not be considered complete until the manuscript submission form has been uploaded/received.
Author Contributions: Authors are required to include a paragraph in the Acknowledgments section listing each author's contribution. Example: "C.K. researched data. L.R. wrote the manuscript and researched data. H.N. reviewed/edited the manuscript. V.S. contributed to discussion and reviewed/edited manuscript. N.B. researched data and contributed to discussion. V.G. wrote the manuscript." In addition, when authors cite the "editorial assistance" of a colleague, or help provided by a colleague "with preparing the manuscript," authors are required to list the employer/institution with which that colleague is affiliated. Example: "The authors acknowledge the editorial assistance of Ali Akbari, Tehran University, etc."; "The authors thank Ali Akbari, Tehran University, for help with preparing the manuscript."
Incomplete or non-conforming work will be sent back to the author to be corrected and may cause delays in the review process. The mission of Molecular Medicine Journal is to publish recent original findings that elucidate the pathogenesis of disease at the molecular or physiological level, which may lead to the design of specific tools for disease diagnosis, treatment, or prevention. Manuscripts containing original material relevant to the genetic, molecular, or cellular basis of key physiologic or disease processes are considered for publication if neither the article nor any part of its essential substance, tables, or figures has been or will be published or submitted elsewhere. Pre-submissions sent by email will not be considered. Articles must be in clear and understandable English. Non-native English authors are encouraged to seek the assistance of an English-proficient colleague, or a communications agency to help improve the clarity and readability of a paper before it is submitted to the journal. No article processing fees are required for publishing in this journal and authors are not required to pay upon acceptance of their paper.
A cover letter should accompany each submission. The cover letter should • include a brief description of the scientific advance and its importance; • identifying the person (with address and telephone/fax number/e-mail) responsible for administrative and scientific issues concerning the manuscript; making it clear that the submitted manuscript has been seen and approved by all authors; making it clear that the work is not under consideration elsewhere; including a statement that all human and/or animal studies were approved by the appropriate institutional committee; including the names and email addresses of three independent potential reviewers; note a pre-submission identification number (if applicable); stating if any figures or images have been adapted or reproduced from prior published work.
Original Articles are expected to present a significant advance in molecular medicine research and should be arranged in the following order: title page, abstract (see below), introduction, "Research Design and Methods," Results," "Discussion," "Acknowledgments," "References," tables (each including a title and legend), figure legends, and figures.
• An abstract is required for all Original Articles. The abstract should be structured, concise and precise and should convey the essential findings of the manuscript. The abstract may not exceed 250 words. It should state the rationale, objectives, findings, and conclusions of the manuscript. References, primary data, and statistical significance should not be presented in the abstract, and nonstandard abbreviations must be defined. Authors are encouraged to include a statement that describes the potential translational impact of the study results.
• The word limit for the main text of Original Articles is 4,000 words. (The total word count excludes the title page, abstract, acknowledgments, references, tables and figures, and table/figure legends.) The main text should be double-spaced with justified margins.
• The article should contain no more than 50 references and the reference section should be single spaced with justified margins.
• The article should contain no more than a combination of eight tables and/or figures.
• Supporting documents/data can be uploaded for review purposes and will not be published. (When uploading, be sure each file is clearly labeled "supporting document/data.") Although an option for Online Supplemental Material is available, authors must provide a statement of justification as to why it is important for submission and publication if eventually accepted.
Brings together and analyzes available information in a specific field. These submissions include a summary of the topic/field, a description of gaps in knowledge of the topic/field, and synthesis of information to form a testable hypothesis. Reviews discuss recent developments in the topic/field and make projections about the future direction of a particular field. In some cases, the Editors may commission Review Articles. Word count is approximately 7000 including abstract [250 words], figures [250 words each], and references).
The Brief Report category can be used for any original research pertinent to the journal. The purpose of the category is to permit publication of very important, high-quality mechanistic studies that can be concisely presented. Brief Reports should be formatted in the following manner:
• An abstract is required for all Brief Reports. (Please follow the formatting guidelines listed under Original Articles.)
• The word limit for the main text of Brief Reports is 2,000 words. (The total word count excludes the title page, abstract, acknowledgments, references, tables and figures, and table/figure legends.)
• The report should contain no more than 25 references and the reference section should be single spaced with justified margins.
• The article should contain no more than a combination of four tables and/or figures.
• Supporting documents/data can be uploaded for review purposes and will not be published.
Commentaries are brief articles presenting the authors' views on a topic of current interest. Commentaries (and Editorials) are by invitation only. Commentaries should be limited to 1,000 words, no more one than table and/or figure, and no more than 20 references.
Letters to the Editor
Letters to the Editor are intended to provide an opportunity to comment on articles published within the previous three months in MMJ. Letters to the Editor are not intended as a platform for presenting unpublished data, research, or observations. Letters do not have abstracts and should not exceed 500 words and maximum 5 references. The inclusion of tables or figures in letters is discouraged. As with all submissions, letters should be double-spaced with 12 pt. Times New Roman font and justified margins. Letters must include a title page with the authors' full names and affiliations and the corresponding author's contact information.
Format: Research Articles
Every manuscript must have an accompanying title page. In addition to the full title, the title page should include a short running title (less than 47 characters and spaces); the first name, middle initial, and last name of each author; the affiliation (in English) of each author during the study being reported; the name, current address, telephone number, fax number, and e-mail address of the corresponding author; and the word count and number of tables and figures. The text on the title page should be center aligned. The main text and tables must be saved in Microsoft Word document format, with 12 pt Times New Roman font, and the main text should double spaced with justified margins. Please do not use headers, footers, or endnotes in your paper.
Manuscripts should be organized as follows:
- Title (and a running title) with authors' names and affiliations, and corresponding author's e-mail address
- Structured abstract
- Key words
- Tables and figures (including images if any)
- Acknowledgements and other relevant information such as source of fund, if any
- Previous publication
- Conflict of interest
Title - a title page must appear as the first page of the manuscript. The title page should include a title, running head, author list, keywords, and contact author information. The title of the paper should be 20 words or less. The title should not include acronyms or abbreviations.
Running Head – this short version of the title should include a maximum of 45 letter spaces.
Author Names - the author(s) list must include: the first name(s); the last/family name(s); the name of the department(s) and institution(s) in which the work was done; the institutional affiliation of each author; and the name, address, telephone number, fax number, and e-mail address of the author responsible for correspondence. Any change in author list (additions/deletions) after paper acceptance must be justified in writing to the Editors. During online submission the full names and e-mail addresses of all the authors are required. If the work is accepted, all authors are required to sign the Open Access Authorization and acknowledgement of Authorship form.
Keywords - five MeSH-Medline keywords not included in the title must be included. For assistance visit: http://www.nlm.nih.gov/mesh/mbrowser.html. Note that preferred expression is indicated by the label "Mesh Heading" and not "Entry Term". The desired terms may be then copied from teh MeSh browser. Another way of finding appropriate headings is to search PubMed to find articles on similar topics, and review the MeSh headings assigned to those articles.
Abstract – (250 words) should include the rationale, objectives, results, and conclusions of the study. The Abstract should read as a single, continuous piece and not be written as a structured abstract (broken into separate sections) for review articles and a structured article (Background, Methods, Results and Conclusion) for Original Research Articles.
Introduction - should discuss appropriate, relevant sources that provide context for the study and help explain how the idea for the study came to be and why it is important. The objective and hypothesis of the study at hand should be explicitly stated in last paragraph of this section. The Introduction section should not include any mention of observed results.
Materials and Methods - this section should include sufficient detail to allow another researcher to repeat the experiment. Descriptions may be ‘in brief’, followed by reference to a previous report using the same procedure, or by detailed description. One sentence referring a reader to a prior publication is insufficient.
General studies should include unambiguous identification of nonbiological materials used (chemicals) including the source of such materials, the types of apparatus used, including model number and manufacturer for specialized equipment, the experimental procedure, including potential hazards, if applicable; and the types of test performed, including statistical tests. Biological studies should include unambiguous identification of genus, species, and strain; the source of any organisms (cell line, animal stock); and age, sex, weight, and condition of organisms as appropriate. Protein molecular weights of DNA marker sizes should be indicated on figure panels showing gel electrophoresis. Microscopy should include the make and model of the microscope. Type, magnification, numerical aperture of the objective lenses and acquisition software are also needed. All micrographs must include an unlabeled scale bar in the image with a description included in the figure legend. Research on animals should include a statement that the protocol was approved by the appropriate institutional committee and complied with the Guide for the Care and Use of Laboratory Animals. Descriptions should include information regarding: the animal: number, age, sex, weight, and life stage, source (supplier), genetic nomenclature, microbial/pathogen status, and information related to preparation and assignment to treatment groups (including control groups); the environment: micro and macroenvironments, diet, water, housing; the method: include aspects of animal care that can affect research outcomes, experimental effects, administration of substances, use of infectious agents, sample acquisition, and euthanasia.
Results- The results section should provide complete details of the experiment that are required to support the conclusion of the study. The results should be written in the past tense when describing findings in the authors'experiments. Previously published findings should be written in the present tense. Results and discussion may be combined or in a separate section. Speculation and detailed interpretation of data should not be included in the results but should be put into the discussion section.
Discussion- should interpret the findings in view of the results obtained in this and in past studies on this topic. In fact, it should be an analytical examination of the study and results rather than a repetition of the information in the results section. It is relevant to compare the results of the study to the findings of similar studies and also to discuss the application of these results to the understanding of disease and the development of tools for disease diagnosis, treatment and prevention. The Results and Discussion sections can include subheadings, and when appropriate, both sections can be combined.
Author Contributions paragraph- This paragraph should list each author's contributions as shown on the manuscript submission forms and should be placed in the Acknowledgments.
Acknowledgments- The acknowledgments are located after the main text and before the reference list. Acknowledgments should contain the author contributions paragraph, brief statements of assistance, the guarantor's name (person or persons taking responsibility for the contents of the article), funding/financial support, and reference to prior publication of the study in abstract form, where applicable.
Disclosure– authors should include any necessary conflicts of interest. If none exist, the following text should be included: “The authors declare they have no competing interests as defined by Molecular Medicine Journal, or other interests that might be perceived to influence the results and discussion reported in this paper".
Footnotes - should be restricted to the title page (affiliations, corresponding author) and within tables. Footnotes on the title page are assigned consecutive superscript numbers (i.e., 1, 2, 3, etc.). Footnotes in tables are assigned consecutive, superscript capital letters (i.e., A, B, C, etc.). References- it should be numbered consecutively as they are cited in the text and listed in parentheses.
References first cited in tables or figure legends must be numbered so that they will be in sequence with references in the text. References should include full titles of the papers with inclusive page numbers (Vancouver style). All authors should be listed when there are five or fewer; when there are six or more, the first author should be listed followed by "et al.'' Abbreviate the names of journals according to PubMed. Spell out names of unlisted journals. If essential, ‘personal communication’ may be incorporated in the appropriate place in the text. References to personal communications must be accompanied by a permission letter from the communicator authorizing publication of the comment. Manuscripts listed as in press should be numbered, but a copy of the text should be submitted along with the manuscript under consideration. Your reference manager (Endnote, Mendeley, Refworks, Microsoft word's reference maager, and etc) have the correct format for each citation type (journal article, book chapter, url, book, conference proceedings, and other types reference types available in your refernce manager)
Tables should be double-spaced on separate pages and included at the end of the text document, with the table number and title indicated. Tables should be created using Word and the "Insert Table" command; please do not use tabs and/or spaces to create tables, columns, or rows. Tables with internal divisions (Tables 1A and B) should be submitted as individual tables, i.e., Tables 1 and 2. Symbols for units should be confined to column headings. Abbreviations should be kept to a minimum and defined in the table legend. Please avoid the use of shading. If a table includes data that require explanation in the legend, apply the following symbol sequence, from top to bottom, left to right: *, †, ‡, §, ||, ¶, #, **, ††, ‡‡, etc.
MMJ uses digital publishing methods throughout the journal production process. If your article is accepted, it will be published in online issue. The following sections provide information on how to format your figures to ensure the best possible reproduction of your images.
Figures should be produced at the size they are to appear in the printed journal. Please make sure your figures will fit in one or two columns in width. Multi-paneled figures should be assembled in a layout that leaves the least amount of blank space. 1 column = 21 picas wide, 3.5 in, 8.9 cm 2 columns = 43 picas wide, 7.1 in, 18 cm
At 100% size, fonts should be 8-10 points and used consistently throughout all figures.
Information on the axes should be succinct, using abbreviations where possible, and the label on the y-axis should read vertically, not horizontally. Key information should be placed in any available white space within the figure; if space is not available, the information should be placed in the legend. In general, figures with multiple parts should be marked A, B, C, etc., with a description of each panel included in the legend rather than on the figure.
Line and bar graph
Lines in graphs should be bold enough to be easily read after reduction, as should all symbols used in the figure. Data points are best marked with the following symbols, again assuring that they will be readily distinguishable after reduction: . In the figure legend, please use words rather than the symbols. Bars should be black or white only, unless more than two datasets are being presented; additional bars should be drawn with clear bold hatch marks or stripes, not shades of gray. Line or bar graphs or flow charts with text should be created in black and white, not shades of gray, which are difficult to reproduce in even tones.
If materials (e.g., figures and/or tables) are taken from other sources, it should be noted in the legend, and the author must be able to provide written permission for reproduction obtained from the original publisher and author.
Figure legends should be clearly numbered and included at the very end of your document and should not be included on the separate figure/image files. Please use words to describe symbols used in the figure.
Abbreviations should be used only when necessary, e.g., for long chemical names (HEPES), procedures (ELISA), or terms used throughout the article. All others must be defined at first use. Abbreviate units of measure only when used with numbers. Abbreviations may be used in tables and figures.
Your manuscript should be submitted under the name of the designated corresponding author's user account (the contact person listed on the title page of the manuscript); the corresponding author is the only author who will receive notification of proof availability. The system automatically recognizes the user account as the corresponding author, even if another name is designated. Be sure to review the proofs of your submitted files after uploading them. Do not upload .pdf files, Excel files, or zipped files (unless you are uploading original source files of figures). You may, however, upload pdf copies of the signed manuscript submission form, which can be found in the Editorial Policies section and must be provided for all manuscript submissions. The text of your manuscript should be prepared using a word processing program and saved as a .doc, .txt, or a .rtf file. When uploading each file, you will be asked to choose a designation from a pull-down menu that describes the content of the file (e.g., "Main Document," "Figure," "Table," etc.). In addition to this designation, please ensure that the name of each file clearly describes the content of the file (e.g., "figure1.tiff," "table2.doc," "coverletter.rtf," etc.).
When submitting a revised manuscript, all changes should be indicated with red font and underlined. Deletions need not be indicated within the article itself but should be noted in the author responses to reviewers. If the "track changes" function of a word processing program is used to show additions and deletions, make sure that all changes are "accepted" before submitting the clean revised version. Once the changes are accepted, deactivate the track changes function before saving and uploading the file. Failure to follow instructions may result in publication delays if your manuscript is accepted.
Accepted manuscripts will be scheduled for publication as soon as possible. The corresponding author will receive notification of acceptance and manuscript proof by e-mail. Corrections should be returned within 24 hours of receipt of the proof. Failure to do so may delay the publication of the article to another issue. If an extension is required, please contact the journal's editorial office or email to firstname.lastname@example.org
All clinical trials submitted to MMJ for consideration of publication must be registered.
• Review manuscript submission requirements
• Include cover letter, detailed as outlined in these author instructions
• Provide first and last names and middle initials of all authors; include highest degree and institutional affiliation
• On title page, include article and abstract word count, number of tables and figures
• Provide an abstract that conforms with author instructions for article type
• Provide text files in Microsoft Word
• Provide text in Times New Roman, 12 pt, and double-spaced
• Provide continuously numbered lines (each page does not start at 1)
• Check all references for accuracy and completeness.
• Title each table and figure
• Include all sources of financial and material support in the Acknowledgments section, including grant numbers as appropriate
• Include in the Methods section any information on institutional review board approval or informed consents.
• Clarify if there is any Conflict of Interest
Submission of a manuscript implies: that if and when the manuscript is accepted for publication, the authors agree to automatic transfer of the copyright to the publisher. Please provide a copyright at the initial submission, unless your submission would be considered incomplete.
All submitted manuscripts are subject to peer review and editorial approval. Articles will be sent to at least three reviewers. The review process is double blind as the reviewers are masked as to the identity of the authors and their affiliation, and so are authors. Authors are usually notified within 1-3 months about the acceptability of their manuscript (depending on the prompt response and providing the required information by corresponding author). Reviewers are selected based on their expertise within the topic area of the submission, and their purpose is to assist the authors and the journal by providing a critical review of the manuscript. On receiving reviewers' comments, authors are requested to send the revised article, and a copy of their reply to the reviewers, including the comment and explaining the replies to questions and changes made to the revised version. Communication regarding a specific manuscript will take place between the journal and designated corresponding author only.
It is essential that corresponding authors supply an email address to which correspondence can be emailed while article is in production.
Word files of edited articles may be sent for checking prior to typesetting. It is essential that these files are checked carefully. Full instructions on how to correct and return the file to the publisher will be attached to the email.
Withdrawal definition: is an action that takes the manuscript out of the review process andplaces it back into the author's dashboard.
Our view regarding withdrawal : In general we do not suggest withdrawal, since it wastes valuable manuscript processing time, money and works invested by publisher.
Pre-review: is a period that an author(s) submit(s) her/his article until to be sent for review.
Peer-review: is a period that manuscript submitted completely into the website and included in the review process.
Review - Final Decision: is a period from the acceptance of an article until to be sent for publication if the article meets the journal standards.
Post-Publication: when a paper is published (online and/or hard copy)
What are compelling reasons?
Bogus caim of authorship
Fradulent use of data or the like
Infringements of professional ethical code
We accept all terms and conditions of COPE about plagiarism and in case, any attempts of plagiarism brought to our attention accompanied with convincing evidence, we act based on flowcharts and workflows based determined in COPE.
Republishing is a case of plagiarism in our journal. Our journal explicitly instructs authors not to submit papers on studies that have already been published elsewhere even in other languages, than English. Especially those articles which are published in local journals (with local languages) are not permitted to submitted in our journal. Previous status of the submitted paper should be mentioned in the cover letter , such as presentation in a national or international congress, is a part of dissertation and thesis, a part of the research findings is published elsewhere (including national or international journal).